- maybe Jo and Alex will be the next to enter parenthood (perhaps even parents before marriage.) I wish they’d give one couple multiples twins or triplets. Hunter Calliope Wilson Karev , Robin Christina Wilson Karev and either Herman Stephen Hunt Karev/Herman Caroline Wilson Karev.
- I think that Owen and Amelia will have a daughter, after marriage. Pierce April Shepard Hunt, Warren Ian Shepard Hunt, Webber Alex Hunt Shepard and Edwina Grey Shepard Hunt.
- maybe a daughter for Avery and Kepner Anderson Catherine Josephine Avery , son Sloan Michael Owen Avery another daughter Shepard Amelia Nicole Avery
- Wilson Mary Pierce (Maggie’s daughter) or Karev Edward Pierce if the show only run that long…